Do you guys ever look up your med interactions at www.drugs.com? I have recently discovered that something as simple as taking aspirin for pain control can affect both my blood pressure meds. When I click the professional button I get this.
"High doses of salicylates may blunt the antihypertensive effects of beta-blockers. The proposed mechanism is inhibition of prostaglandin synthesis. Low-dose aspirin does not appear to affect blood pressure. In addition, beta-blockers may exert an antiplatelet effect, which may be additive with the effects of some salicylates. Metoprolol may also increase aspirin absorption and/or plasma concentrations of salicylates; however, the clinical significance of this effect is unknown. Data have been conflicting. Until more information is available, patients who require concomitant therapy should be monitored for altered antihypertensive response whenever a salicylate is introduced or discontinued, or when its dosage is modified."
This is the consumer info on my other blood pressure med, which has a moderate interaction warning.
"Talk to your doctor before using losartan together with aspirin. Combining these medications may reduce the effects of losartan in lowering blood pressure. In addition, these medications may affect your kidney function, especially when they are used together frequently or chronically. You are more likely to develop impaired kidney function during treatment with these medications if you are also using a diuretic ("water pill") or if you are elderly or have preexisting kidney disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor."
This is from clicking the professional button.
"Concomitant use of NSAIDs and angiotensin II receptor antagonists may cause deterioration in renal function, particularly in patients who are elderly or volume-depleted (including those on diuretic therapy) or have compromised renal function. Acute renal failure may occur, although effects are usually reversible. Chronic use of NSAIDs alone may be associated with renal toxicities, including elevations in serum creatinine and BUN, tubular necrosis, glomerulitis, renal papillary necrosis, acute interstitial nephritis, nephrotic syndrome, and renal failure. Additionally, in patients with prerenal conditions whose renal perfusion may be dependent on the function of prostaglandins, NSAIDs may precipitate overt renal decompensation via a dose-related inhibition of prostaglandin synthesis. Angiotensin II receptor antagonists can further worsen renal function by blocking the effect of angiotensin II-mediated efferent arteriolar vasoconstriction, thereby decreasing glomerular filtration."
Do you agree that it's a good idea to do your own research?
I look up tons of stuff constantly, but that's the first time I looked up those med combos. Since I haven't used tylenol since 2014 and my pain med choices are continuing to dwindle away, I'm down to basic aspirin as first choice. I've been electing to forego any kind of pain treatment for anything less than immediately agonizing because it's becoming easier and easier to see I'm the one spiking blood pressure with meds. Doctors have responded for years that my BP spikes are a pain response, not one of them has looked into possibly a pain MED response.
I've also been keeping thoughts on a back burner that a med combo of blood pressure med, aspirin, and benadryl contributes to increased apneas while I'm sleeping. Some nights are beautifully smooth, others are disastrous, and the only commonalities left in my observations are evenings that I do or don't treat for allergies and/or pain.
I've moved benadryl up to mid afternoon, none before bed, and I had moved full-dose aspirin diametrically opposite of losartan on the clock if I feel I really need it, and I seem to be gaining more and more and more control over adverse anything. I'm going to hold at this the rest of spring and see if it truly retains any kind of conclusive integrity.
They started me on very heavy meds in my 20s for autoimmune flares and severe fibromyalgia pain, kept me heavily dosed for ten full years until a passing endocrinologist rang the alarm to get off meds because harm to my liver, and after that was another 15 years of undiagnosed diabetes and offers of more and more meds from a variety of specialists who'd have likely been more able to help me if my primary back then had simply dx'd the diabetes, and since 2011 it's been a mess of untangling what exactly is doing what to the point where a group of specialists had to crash me off supplemental hormones getting blood pressure controlled, and that entire time no one questioned renal damage showing up, no one addressed vitamin and mineral deficiencies (low magnesium sucketh in ways you do not want to know, including risk of death), and even though my current doctor is finally addressing possibly years of vitamin D deficiency and stabilized renal damage, we're still not addressing a constant low blood sodium, which could be a problem on losartan.
It's a little late to be the healthiest I've ever been in my adult life, but I'll certainly take it, and damn betcha I'm not risking making it worse again, even with aspirin for low level chronic pain. Give me ice packs and heating pads, I'll keep doing my stretches and core strength workouts, and if I need more help I'll call a massage therapist.
In the meantime, I also happen to know that aspirin and beta blockers increase histamines, and I'm currently in my highest histamine time of year with oak pollen all over, so I feel like taking extra precautions avoiding foods and meds that spike blood histamine levels is really smart. I'm doing afrin spray as needed and going through bottles of saline mist and tubes of ayr gel, so benadryl is held to a minimum, and I'm learning that dehydration from benadryl is NOT best treated with chugging extra water when you have a history of mild renal damage and a family history of congestive heart failure. Backed up water processing spikes blood pressure, adds overall weight, and sometimes increases my arthritic pain.
Side note. Masking does NOT hold outdoor allergies down. Wrap your little minds around that one. Also, masking makes sinus infections from outdoor allergies monumentally worse, as I found out last year. I'm electing to go maskless as often as possible. If I have to put one on to enter a building, so be it, but if I feel like taking it off, I'm taking it off. If someone flips out all over me, I can put it back on to calm their immediate anxiety (that has happened), but otherwise I feel like the bulk of the world has been trained to park their brains at any and every door and ignore common sense. Not being able to think through noticing that masks don't stop strep and outdoor allergies is the biggest red flag I can think of that brains have been retrained via mass mainstream medias not to be able to logically think and problem solve beyond being told what to do. And doctors going along with this are complicit. Years of medical school undone with mass blanket hypochondria and superstition.
Twitter abruptly logged me out of all my accounts across all my devices right after I posted this alert, and I haven't been able to log back in since then. I looked at downdetector and discovered this has been happening to a number people. I'm wondering if IPs are being blacklisted now. Anyway, there were 9 other screenshots, and my laptop is absolutely refusing to load them completely, like they're cut off, and even pasting carries that mutilated copy over.
From https://inteldinarchronicles.blogspot.com/2021/04/restored-republic-via-gcr-update-as-of_17.html
So in case you don't click over to source or my twitter, we got the alert that the current internet going away is imminent.
D. Fri. 16 April Whiplash347 Telegram:
XX also = 1010. On The Clock
ON THE CLOCK Means that they will be shutting down Social Media then Internet via Flooding the net with Evidence then cyber attacks & Fake Nuclear Scare Event. Before we go to EBS. We get the new Quantum Internet. This current internet will be wiped. All ties back to 1871 Act of England reversal & Operation Mockingbird. Mr Pool did earlier warn us about IRAN.
Lexington and Concord: The shot heard round the world. April 19 1775 The Shot Heard Around The World As The World Turns. On The Clock. Write these 3^ In Qagg.news These next coming days to the 20th are the "BE ALL & END ALL" of this entire time we are living.
The IRS is saying prepare for debt cancellation.
Mr Pool Black swan event.....A black swan is an unpredictable event that is beyond what is normally expected of a situation and has potentially severe consequences. Black swan events are characterized by their extreme rarity, severe impact, and the widespread insistence that were obvious in hindsight.
Black swan event will be the start of the new ISO flare network monetary family. Everything is ready for the switch. From > To: Swift > Quantum Financial System BTC > Blockchain ISO regulated asset backed metals MSM > Starlink & Project Odin $€ > Gold Dark to Light
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